Familial Mediterranean Fever (FMF) before the age of one year
نویسندگان
چکیده
Results We identified 446 patients divided as such: 37 in the earlyonset group (A) and 409 in the other group (B). A statistically significant difference was noted between the 2 groups (A vs B) for the ethnic origin (Sefaradic Jews p < 0.001), male preponderance (p < 0.015), number of crises/month (p < 0.015), response to colchicine treatment, and type of mutations in codon 694 and 680 (for M694V, p < 0.04).
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Background Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disorder caused by mutations in the MEFV gene. The disease is especially common among Mediterranean ancestry, mostly Armenian, Turkish, Jewish and Arab populations. We aimed to describe genotype pattern of FMF in the Jordanian children and to compare it with other populations. Materials and Methods A retros...
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